Electric Literature of C21H16N2. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 2,4,5-Triphenylimidazole, is researched, Molecular C21H16N2, CAS is 484-47-9, about An eco-friendly, one pot synthesis of tri-substituted imidazoles in aqueous medium catalyzed by RGO supported Au nano-catalyst and computational studies.
An eco-compatible, mild and operationally simple aqueous phase protocol for the synthesis of 2,4,5-trisubstituted imidazoles I [Ar = Ph, 2-MeC6H4, 2-naphthyl, etc.] was developed with high substrate scope using supported Au nanoparticles. The catalyst could be recovered for the subsequent reactions and reused without any appreciable loss. The utility of this protocol was further explored to synthesis of fused and structurally versatile imidazole also. The synthetic attributes of imidazoles were also demonstrated through the computational studies. Furthermore, low E-factor and process mass intensity made the this method more sustainable as compared to earlier literature reports.
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Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts