So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Shafaati, A.; Clark, B. J. researched the compound: 5-Chloro-1-methyl-4-nitroimidazole( cas:4897-25-0 ).Recommanded Product: 4897-25-0.They published the article 《Determination of azathioprine and its related substances by capillary zone electrophoresis and its application to pharmaceutical dosage forms assay》 about this compound( cas:4897-25-0 ) in Drug Development and Industrial Pharmacy. Keywords: azathioprine determination pharmaceutical capillary zone electrophoresis; imidazole azathioprine determination capillary zone electrophoresis. We’ll tell you more about this compound (cas:4897-25-0).
The development of a stability-indicating capillary zone electrophoresis (CZE) method for the determination of azathioprine (AZA) and its related substances in bulk and dosage forms is described. Theophylline was used as an internal standard to improve quant. results. The method was fully validated in terms of repeatability (RSD for migration time and peak area ratio were 0.15 and 0.60%, resp.), reproducibility (RSD of peak area ratio was 0.84%), linearity at 2 ranges of the azathioprine concentration, limits of detection and quantitation, and robustness. The method was applied for determination of the drug in bulk and a com. tablet dosage form (recovery 98.3-101.3%) and in powder for injection (recovery 98.7-100.6%). The method was fast and reliable for the determination of AZA and its related substances in bulk and dosage forms.
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Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts