Application In Synthesis of Pyridine-4-thiol. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: Pyridine-4-thiol, is researched, Molecular C5H5NS, CAS is 4556-23-4, about Mercaptopyridine-Functionalized Gold Nanoparticles for Fiber-Optic Surface Plasmon Resonance Hg2+ Sensing. Author is Yuan, Huizhen; Ji, Wei; Chu, Shuwen; Liu, Qiang; Qian, Siyu; Guang, Jianye; Wang, Jiabin; Han, Xiuyou; Masson, Jean-Francois; Peng, Wei.
As a highly toxic heavy metal ion, divalent mercuric ion (Hg2+) is one of the most widely diffused and hazardous environmental pollutants. In this work, a simple, portable, and inexpensive fiber-optic sensor based on surface plasmon resonance (SPR) effect was developed for Hg2+ detection, which takes advantage of 4-mercaptopyridine (4-MPY)-functionalized Au nanoparticles (Au NPs/4-MPY) as a signal amplification tag. Based on the coordination between Hg2+ and nitrogen in the pyridine moiety, we developed the sensor by self-assembling 4-MPY on Au film surfaces to capture Hg2+ and then introducing Au NPs/4-MPY to generate a plasmonic coupling structure with the configuration of nanoparticle-on-mirror. The coupling between localized SPR increased changes in SPR wavelength, which allowed highly sensitive Hg2+ sensing in aqueous solution The sensor exhibited superior selectivity for Hg2+ detection compared with other common metal ions in water. The sensor’s Hg2+ detection limit is 8 nM under optimal conditions. Furthermore, we validated the sensor’s practicality for Hg2+ detection in tap water samples and demonstrated its potential application for environmental water on-site monitoring.
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Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts