Electric Literature of 1591-37-3, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1591-37-3, name is 2-Amino-6-methoxybenzonitrile belongs to nitriles-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
EXAMPLE 46 9-Amino-8-methoxy-4-oxa-1,2,3,4-tetrahydroacridine Following the method of Example 7, but substituting 2-amino-6-methoxybenzonitrile for anthranilonitrile afforded the title compound (11%, m.p. 205-207 C.). 1 H-NMR (CDCl3, 300 MHz,delta): 2H, m, 7.33 ppm; 1H, dd, 6.57 ppm (J=3, 6 Hz); 2H, bs, 5.92 ppm; 2H, t, 4.29 ppm (J=2, 6 Hz); 3H, s, 3.95 ppm; 2H, t, 2.5 ppm (J=2, 6 Hz); 2H, m, 2.13-2.07 ppm; TLC: (90:10:1-methylene chloride:methanol:28% aqueous ammonia) Rf -0.49.
The synthetic route of 2-Amino-6-methoxybenzonitrile has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Pfizer Inc.; US5202440; (1993); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts