Adding a certain compound to certain chemical reactions, such as: 68119-31-3, name is 2-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)acetonitrile, belongs to nitriles-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 68119-31-3, Formula: C9H5F2NO2
288 g of water and 67 g of triethylamine were placed in the reaction tank.Stir well, add 4g of tetraoctyl ammonium bromide and 44g of 2,2-difluoro pepper acetonitrile.80 g of 1-bromo-2-chloroethane was added dropwise at 35 C, and the reaction was kept at 35 C for 1 h, and the reaction was completed, and the solid product was directly filtered to obtain the target product, which was 48 g after drying.After HPLC purification,The content of 1-(2,2-difluorobenzo[D][1,3]dioxol-5-yl)cyclopropylcarbonitrile is 99.6%,The yield was 96.3%.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)acetonitrile, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Fuxin Aoruikai New Materials Co., Ltd.; Liu Min; Yang Yinxing; Chen Li; Liu Chunyu; Liu Wei; Qin Wenyi; (7 pag.)CN105130949; (2019); B;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts