In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 17626-40-3, name is 3,4-Diaminobenzonitrile belongs to nitriles-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. HPLC of Formula: C7H7N3
General procedure: To a methanolic solution of the hydrogenated product 1 (0.40 g, 3.06 mmol), equivalent amount of 2,4-difluorobenzaldehyde (0.44 mL, 3.06 mmol) and half equivalent of aqueous solution of Na2S2O5 (0.29 g, 1.53 mmol in 3 mL H2O) were added. The resulting solution was stirred at reflux for 5 h, and filtered through a bed of Celite. The filtrate was concentrated under reduced pressure and residue was purified by column chromatography (eluent pet. ether/EtOAc, 7:3). The pure product was isolated as a solid (0.46 g, 1.83 mmol 65% yield)
The synthetic route of 17626-40-3 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Singh, Manish; Tandon, Vibha; European Journal of Medicinal Chemistry; vol. 46; 2; (2011); p. 659 – 669;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts