Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 622-75-3, name is 2,2′-(1,4-Phenylene)diacetonitrile, This compound has unique chemical properties. The synthetic route is as follows., Formula: C10H8N2
Add p-hydroxybenzaldehyde (0.01 mol, 1.22 g) and epichlorohydrin (0.10 mol, 9.25 g) to a 250 mL single-necked bottle with magnets, heat up to 68 C, and add tetrabutyl dibutyl ether after the raw materials are dissolved. Ammonium bromide (0.001mol, 0.322g). After 8 hours of reaction, terephthalonitrile (0.0045mol, 0.7000g) and 150mL of ethanol were added. After stirring for 10 minutes, solid sodium hydroxide (0.03mol, 1.20g) was added. , Continue the reaction for 4 to 6 hours and stop the reaction.After the temperature of the reaction system dropped to room temperature, suction filtration was performed to collect the solid product, washed with water, and dried to obtain a crude product. The crude product was recrystallized from a mixed solvent of DMF and ethanol (V: V = 3: 1) to obtain a pure yellow product 1.95. g, yield 93%.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 622-75-3.
Reference:
Patent; Xiangtan University; Zhang Hailiang; Tan Huiping; Yuan Yongjie; Yang Bohao; (15 pag.)CN110407772; (2019); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts