Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 3759-28-2, name is 2-(Cyanomethyl)benzonitrile, This compound has unique chemical properties. The synthetic route is as follows., Computed Properties of C9H6N2
Step 1) (1116) To alpha-cyano-o-tolunitrile (1.5 g, 10.55 mmol) and benzyltributylammonium bromide (0.150 g, 0.42 mmol) in 8N aqueous sodium hydroxide solution (26.4 mL, 211.03 mmol) was added 1,4-butylene bromide (1.449 mL, 12.13 mmol) at room temperature, and the mixture was stirred overnight at room temperature. To the reaction mixture was added water, and the mixture was extracted with ethyl acetate. The organic layer was washed with saturated brine, and dried over magnesium sulfate, and the solvent was evaporated under reduced pressure to give crude 2-(1-cyanocyclopentyl)benzonitrile (2.69 g, 13.71 mmol, 130%) as a brown oil. 1H-NMR(300MHz,CDCl3):delta1.98-2.18(4H,m),2.26-2.44(2H,m),2.59-2.79(2H,m),7.38-7.50(1H,m),7.62(1H,td,J=7.8,1.5Hz),7.67-7.83(2H,m).
According to the analysis of related databases, 3759-28-2, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Takeda Pharmaceutical Company Limited; YAMAMOTO, Satoshi; SHIRAI, Junya; FUKASE, Yoshiyuki; SATO, Ayumu; KOUNO, Mitsunori; TOMATA, Yoshihide; OCHIDA, Atsuko; YONEMORI, Kazuko; ODA, Tsuneo; IMADA, Takashi; YUKAWA, Tomoya; (238 pag.)EP2975031; (2016); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts