Adding a certain compound to certain chemical reactions, such as: 874-89-5, name is 4-(Hydroxymethyl)benzonitrile, belongs to nitriles-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 874-89-5, Quality Control of 4-(Hydroxymethyl)benzonitrile
In a 10 mL round bottom flask, 0.66 g of 4-cyanobenzyl alcohol and 2 g of diethylene glycol dimethyl ether were sequentially added.The resulting mixture was subjected to ultrasonic irradiation at 40 kHz/30 W/70 C for 30 minutes in an ultrasonic reaction apparatus. The diethylene glycol dimethyl ether was removed under reduced pressure, and recrystallized to give 0.68 g of 4-cyanobenzoic acid, yield 93%.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 4-(Hydroxymethyl)benzonitrile, and friends who are interested can also refer to it.
Reference:
Patent; Central South University; Xiao Fang; Xiao Yuanyuan; Zeng Ming; Li Na; Yin Lirong; (15 pag.)CN108467342; (2018); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts