Some tips on 1080-74-6

Statistics shows that 1080-74-6 is playing an increasingly important role. we look forward to future research findings about 2-(3-Oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile.

1080-74-6, name is 2-(3-Oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile, belongs to nitriles-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. 1080-74-6

Take a two-necked round bottom flask, dissolve compound 8-1 in chloroform, and perform a Knoevenagel condensation reaction with malononitrile indanone ketone electronic unit under weakly basic conditions. After TLC monitors the reaction, directly use reaction oil The ether / dichloromethane eluent was passed through the column to obtain the final type of organic solar cell using diindenobisthiophene as the core; wherein, the compound 8-1, the electron-drawing unit, pyridine, and chloroform had a ratio of 0.2 to 2.2mmol: 0.3 3.0mmol: 0.01 0.5mmol: 10 50mL; yield is 84.7%;

Statistics shows that 1080-74-6 is playing an increasingly important role. we look forward to future research findings about 2-(3-Oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile.

Reference:
Patent; Xiamen University; Xie Suyuan; Zheng Shanyu; An Mingwei; Pei Yaqian; Deng Linlong; (31 pag.)CN110746440; (2020); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts