In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 868-54-2 as follows. Application In Synthesis of 2-Aminoprop-1-ene-1,1,3-tricarbonitrile
General procedure: A mixtureof 1 mmol of the corresponding aromatic aldehyde, 0.132 g (1 mmol) of malononitrile dimer, 0.125 g (0.2 mmol) of Triton X-100, and one drop of triethylamine in 5 mL of water was stirred at room temperature until the reaction was complete (TLC). The precipitate was ground with water, filtered off, washed with water, and recrystallized from propan-2-ol.
According to the analysis of related databases, 868-54-2, the application of this compound in the production field has become more and more popular.
Reference:
Article; Ershov; Bardasov; Alekseeva, A. Yu.; Ievlev, M. Yu.; Belikov, M. Yu.; Russian Journal of Organic Chemistry; vol. 53; 7; (2017); p. 1025 – 1029; Zh. Org. Khim.; vol. 53; 7; (2017); p. 1014 – 1018,5;,
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