Application of 2,2′-(1,4-Phenylene)diacetonitrile

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2,2′-(1,4-Phenylene)diacetonitrile, other downstream synthetic routes, hurry up and to see.

622-75-3, A common compound: 622-75-3, name is 2,2′-(1,4-Phenylene)diacetonitrile, belongs to nitriles-buliding-blocks compound, it can change the direction of chemical reaction, and react with certain compounds to generate new functional products. A new synthetic method of this compound is introduced below.

Weigh 1,4-benzenediacetonitrile 0.807 g (5.17 mmoL) was dissolved in 20 mL of ethanol,Add NaOH for 0.5h, weighed the first step of the synthesis of the product 3g (10.3mmoL) added to the flask for 3h,The reaction solution was washed with saturated brine and dried over anhydrous sodium sulfate. After filtration, the solvent was distilled off under reduced pressure,To give 2.75 g of a pale yellow solid;

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2,2′-(1,4-Phenylene)diacetonitrile, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Hefei University of Technology; LU, HONG BO; ZHANG, SHAN NA; YANG, JIA XIANG; LU, GUO QIANG; QIU, LONG ZHEN; ZHANG, GUI YU; XU, WEI; (11 pag.)CN103641742; (2016); B;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts