Adding a certain compound to certain chemical reactions, such as: 21524-39-0, name is 2,3-Difluorobenzonitrile, belongs to nitriles-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 21524-39-0, Quality Control of 2,3-Difluorobenzonitrile
General procedure: A solution of 2 (1 mmol) and 3(1 mmol) in anhydrous DMF (10 mL) containing anhydrous K2CO3 (2 mmol) was heated at a given temperature for 2-36 h. DMF was removed in vacuo and the residue was dissolved in chloroform (10 mL). This solution was extracted with 5% HCl (2 x 5 mL). The combined aqueous extracts were neutralized with 10% aqueous NaOH to pH 8 and the resulting precipitate was filtered off, washed with water and dried in vacuo at 50 C for 24 h to provide analytically pure title compounds.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2,3-Difluorobenzonitrile, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Karamysheva, Kseniya; Reutskaya, Elena; Sapegin, Alexander; Dorogov, Mikhail; Krasavin, Mikhail; Tetrahedron Letters; vol. 56; 41; (2015); p. 5632 – 5636;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts