Reference of 874-97-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 874-97-5, name is 3-Cyanobenzyl alcohol belongs to nitriles-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
General procedure: Procedure 2: In a vial the acid (1.32 mmol), dicyclohexylcarbodiimide (DCC; 1.45 mmol) and the alcohol (1.32 mmol) were dissolved in dry THF (5mL). The reaction mixture was stirred at room temperature overnight, and then filtered. The filtrate was diluted with dichloromethane and washed with water (2x) followed by brine, dried over sodium sulfate and concentrated to a crude residue, which was purified by flash chromatography.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3-Cyanobenzyl alcohol, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Titchenell, Paul M.; Hollis Showalter; Pons, Jean-Francois; Barber, Alistair J.; Jin, Yafei; Antonetti, David A.; Bioorganic and Medicinal Chemistry Letters; vol. 23; 10; (2013); p. 3034 – 3038;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts