Application of 873-32-5, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 873-32-5, name is 2-Chlorobenzonitrile, This compound has unique chemical properties. The synthetic route is as follows.
General procedure: Aryl chloride (1.0 mmol), phenylboronic acid (1.5 mmol),PdPAN-Ad-0.5 catalyst (13.7 mg, 0.075 mol% Pd), K2CO3(280.5 mg, 2.0 mmol) and i-PrOH/water (2.0 mL, 1:1 volumeratio) were added to a 20-mL pressure tube under argon. After the tube was heated at 100 C for 18 h with stirring in an oilbath, the reaction mixture was cooled to room temperature.The crude product was purified by column chromatography onsilica gel and analysed by 1H NMR spectroscopy to confirm the product.
The chemical industry reduces the impact on the environment during synthesis 2-Chlorobenzonitrile. I believe this compound will play a more active role in future production and life.
Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts