Reference of 622-75-3, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 622-75-3, Name is 2,2′-(1,4-Phenylene)diacetonitrile, SMILES is N#CCC1=CC=C(CC#N)C=C1, belongs to nitriles-buliding-blocks compound. In a article, author is Song, Dingguo, introduce new discover of the category.
Ruthenium catalyzed alpha-methylation of sulfones with methanol as a sustainable C1 source
Methylation of sulfones, which have an alpha-CH bond, can be easily achieved via a one-step, Ru(II) catalyzed redox neutral reaction using methanol as a sustainable C1 building block. The reaction requires a stoichiometric amount of base and generates only water as a byproduct. A series of value-added methylated sulfones with various functional groups are produced under the reaction conditions from readily available substrates. Mechanism studies shows that a sulfone carbanion addition to an in situ generated aldehyde formed via catalytic dehydrogenation and subsequent catalyst mediated reduction of the alkene by hydrogen may be involved.
Reference of 622-75-3, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 622-75-3.