Chemistry is an experimental science, Application In Synthesis of 2-Bromoacetonitrile, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 590-17-0, Name is 2-Bromoacetonitrile, molecular formula is C2H2BrN, belongs to nitriles-buliding-blocks compound. In a document, author is Mouhsine, Bouchaib.
Efficient and Clean Nickel Catalyzed alpha-Allylation Reaction of Nitriles
A clean method has been developed for the a-allylation of phenyl and alpha alkyl phenyl acetonitrile with allylic alcohols. The reaction is catalyzed by nickel complexes in situ generated from a combination of Ni(cod) 2 and the dppf ligand and performed at 80 degrees C in methanol as reaction solvent. Accordingly to this simple and base-free protocol that only yields water as a side-product, many allylic nitriles were synthetized with good yields.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 590-17-0, in my other articles. Application In Synthesis of 2-Bromoacetonitrile.