Related Products of 403-54-3, The chemical industry reduces the impact on the environment during synthesis 403-54-3, name is 3-Fluorobenzonitrile, I believe this compound will play a more active role in future production and life.
A solution of 3-F-benzonitrile (8.2 g, 68 mmol) and N-methylpiperazine (41.5 mL, 374 mmol) in anhydrous DMSO (60 mL) was warmed at 100 C. with stirring for 28 h. After cooling the reaction mixture was poured into water (600 mL) and was extracted with diethylether (3¡Á500 mL). The organic phase was washed with brine, dried over sodium sulfate and concentrated to give 3-(4-methylpiperazin-1-yl)benzonitrile as an oil (10.3 g, 51.2 mmol, 75%).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3-Fluorobenzonitrile, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Pharmacia Italia S.p.A.; US2007/112020; (2007); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts