A simplified method to prepare 2-amino-5-bromopyrimidine. A laboratory experiment was written by Fichter, Richard;Bonvicino, Guido E.. And the article was included in Journal of Chemical Education in 1985.Quality Control of 2-Aminopyrimidine-5-carbonitrile This article mentions the following:
An experiment for undergraduate organic chem. students is described in the preparation of 2-amino-5-bromopyridine by the bromination of 2-aminopyrimidine. The preparation of 2-amino-5-cyanopyrimidine from 2-amino-5-bromopyrimidine is also described. In the experiment, the researchers used many compounds, for example, 2-Aminopyrimidine-5-carbonitrile (cas: 1753-48-6Quality Control of 2-Aminopyrimidine-5-carbonitrile).
2-Aminopyrimidine-5-carbonitrile (cas: 1753-48-6) belongs to nitriles. Nitrile function is a very important functional group because it can be manipulated to other functional groups such as carboxylic acid by hydrolysis or amine by reduction, respectively. Nitrile groups in organic compounds can undergo a variety of reactions depending on the reactants or conditions. A nitrile group can be hydrolyzed, reduced, or ejected from a molecule as a cyanide ion.Quality Control of 2-Aminopyrimidine-5-carbonitrile
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts