Liquid-crystalline compounds. X. trans-4-Cyanocyclohexanol derivatives with liquid-crystalline properties was written by Praefcke, Klaus;Schmidt, Dietmar. And the article was included in Chemiker-Zeitung in 1981.HPLC of Formula: 24056-34-6 This article mentions the following:
Nine trans-4-cyanocyclohexyl esters (I and II, R1 = C5H11, C7H15, C9H19; and III, R2 = Pr, C5H11, C7H15) were prepared by converting the appropriate carboxylic acids into their acid chlorides and esterifying them with trans-4-cyanocyclohexanol; the esters exhibited both nematic and isotropic liquid crystal phases. cis-4-Cyanocyclohexyl trans–p-(4-propylcyclohexyl)benzoate, which showed a nematic phase, was prepared similarly. In the experiment, the researchers used many compounds, for example, 4-Hydroxycyclohexanecarbonitrile (cas: 24056-34-6HPLC of Formula: 24056-34-6).
4-Hydroxycyclohexanecarbonitrile (cas: 24056-34-6) belongs to nitriles. The R-C-N bond angle in and nitrile is 180° which give a nitrile functional group a linear shape. Both the carbon and the nitrogen are sp hydridized which leaves them both with two p orbitals which overlap to form the two π bond in the triple bond. In addition, Nitriles can react with alkynes, which leads to an increase in carbon chain length (carbocyanation).HPLC of Formula: 24056-34-6
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts