Kim, Youyoung et al. published their research in Chemical Communications (Cambridge, United Kingdom) in 2021 | CAS: 1483-54-1

2-Amino-4-(trifluoromethyl)benzonitrile (cas: 1483-54-1) belongs to nitriles. The electronic structure of nitriles is very similar to that of an alkyne with the main difference being the presence of a set of lone pair electrons on the nitrogen. In addition, Nitriles can react with alkynes, which leads to an increase in carbon chain length (carbocyanation).Safety of 2-Amino-4-(trifluoromethyl)benzonitrile

Ir(III)-Catalysed electrooxidative intramolecular dehydrogenative C-H/N-H coupling for the synthesis of N-H indoles was written by Kim, Youyoung;Kim, Dongwook;Chang, Sukbok. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2021.Safety of 2-Amino-4-(trifluoromethyl)benzonitrile This article mentions the following:

An iridium(III)-catalyzed electrooxidative intramol. dehydrogenative C-H/N-H coupling of unprotected 2-alkenyl anilines was described. The developed method allowed the synthesis of a variety of 3-substituted N-H indole scaffolds under undivided electrolytic conditions. Mechanistic studies suggested that the reaction proceeds through the electro-oxidation induced reductive elimination pathway. In the experiment, the researchers used many compounds, for example, 2-Amino-4-(trifluoromethyl)benzonitrile (cas: 1483-54-1Safety of 2-Amino-4-(trifluoromethyl)benzonitrile).

2-Amino-4-(trifluoromethyl)benzonitrile (cas: 1483-54-1) belongs to nitriles. The electronic structure of nitriles is very similar to that of an alkyne with the main difference being the presence of a set of lone pair electrons on the nitrogen. In addition, Nitriles can react with alkynes, which leads to an increase in carbon chain length (carbocyanation).Safety of 2-Amino-4-(trifluoromethyl)benzonitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts