Liu, Min published the artcilePd-Catalyzed Asymmetric Acyl-Carbamoylation of Alkene to Construct α-Quaternary Chiral Cycloketone, Synthetic Route of 68569-14-2, the publication is Organic Letters (2021), 23(16), 6299-6304, database is CAplus and MEDLINE.
The palladium-catalyzed asym. acyl-carbamoylation of alkene by employing thioesters as acyl electrophiles and t-BuNC as carbamoyl reagent, affording α-quaternary chiral cycloketones I [R = Me, Ph, 3-FC6H4, etc.; R1 = 4-Me, 5-Cl, etc.] and II [Ar = Ph, 4-FC6H4, 3-MeOC6H4, etc.] in synthetically useful yields with excellent enantioselectivity was reported. The reaction proceeded via asym. 1,2-migratory insertions of acyl-Pd to alkenes and subsequent migratory insertion of isocyanides to C(sp3)-PdII. The product could be diversified to some valuable skeletons with retention of enantiopurity, demonstrating synthetic utility of this protocol.
Organic Letters published new progress about 68569-14-2. 68569-14-2 belongs to nitriles-buliding-blocks, auxiliary class Palladium, name is Tetrakis(acetonitrile)palladium(II) Ditriflate, and the molecular formula is C10H12F6N4O6PdS2, Synthetic Route of 68569-14-2.
Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts