Hikawa, Hidemasa published the artcileCationic palladium(II)-catalyzed dehydrative nucleophilic substitutions of benzhydryl alcohols with electron-deficient benzenethiols in water, Application In Synthesis of 68569-14-2, the publication is Organic & Biomolecular Chemistry (2016), 14(29), 7038-7045, database is CAplus and MEDLINE.
An efficient direct nucleophilic substitution of benzhydryl alcs. with electron-deficient benzenethiols using cationic Pd(II) catalysts as Lewis acids in water is reported. Atom economical and environmentally benign protocols afford S-benzylated products in moderate to excellent yields. Com. available Pd(MeCN)4(OTf)2, PdCl2(MeCN)2, and Na2PdCl4 are highly efficient catalysts. Notably, this simple protocol can be achieved without any other additives such as acids, bases, or external ligands. A Hammett study on the rate constants of S-benzylation by using various substituted benzhydryl alcs. yielded neg. ρ values, suggesting that there is a build-up of pos. charge in the transition state.
Organic & Biomolecular Chemistry published new progress about 68569-14-2. 68569-14-2 belongs to nitriles-buliding-blocks, auxiliary class Palladium, name is Tetrakis(acetonitrile)palladium(II) Ditriflate, and the molecular formula is C10H12F6N4O6PdS2, Application In Synthesis of 68569-14-2.
Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts