Zhou, Meng published the artcileA Metal-Free Three-Component Reaction of trans-β-Nitrostyrene Derivatives, Dibromo Amides, and Amines Leading to Functionalized Amidines, COA of Formula: C9H6N2O2, the publication is Journal of Organic Chemistry (2019), 84(2), 1015-1024, database is CAplus and MEDLINE.
Amidines such as I were prepared chemoselectively and diastereoselectively by three-component reactions of β-nitrostyrenes such as (E)-PhCH:CHNO2 with BocNBr2 or with N,N-dibromoamides generated in situ from amides and N-bromosuccinimide or N-chlorosuccinimide. A bisamidine and α,β-unsaturated amidines were prepared using this method. The mechanism of formation of I was studied by isolation of reaction intermediates and their further reaction; the α,α-dibromonitroalkane PhCH(NHBoc)CBr2NO2 [formed by addition of BocNBr2 to (E)-PhCH:CHNO2] underwent elimination to (Z)-PhC(NHBoc):CBrNO2 which underwent C-C bond cleavage in the presence of base and morpholine to yield I.
Journal of Organic Chemistry published new progress about 5153-73-1. 5153-73-1 belongs to nitriles-buliding-blocks, auxiliary class Nitrile,Alkenyl,Nitro Compound,Benzene, name is (E)-4-(2-Nitrovinyl)benzonitrile, and the molecular formula is C8H6ClNO, COA of Formula: C9H6N2O2.
Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts