Jaiswal, Pradeep Kumar published the artcileStereoselective synthesis of highly functionalized tetrahydrocarbazoles through a domino Michael-Henry reaction: an easy access to four contiguous chiral centers, Recommanded Product: (E)-4-(2-Nitrovinyl)benzonitrile, the publication is RSC Advances (2013), 3(27), 10644-10649, database is CAplus.
For the first time, a very simple, efficient, mild, catalytic and one-step procedure for the synthesis of a series of densely functionalized 1-methoxycarbonyl-2-aryl-3-nitro-4-hydroxy-1,2,3,4-tetrahydro-9H-carbazole derivatives was achieved by a domino Michael reaction-Henry reaction (tandem reaction) of Me 3-formyl-1H-indole-2-acetic acid esters and β-nitrostyrene derivatives using 1,4-diazabicyclo[2.2.2]octane (DABCO) as an organocatalyst. Furthermore, high enantioselectivity (92% enantiomeric excess) and diastereoselectivity (≤12:1 dr) were observed with a chiral organocatalyst and thus, the synthesis of the target compounds was achieved in excellent yield using 9-(benzyl)cupreidine (10 mol%) as catalyst. The title compounds thus formed included a tetrahydro(hydroxy)(nitro)(phenyl)carbazolecarboxylic acid ester derivative (I) and related substances.
RSC Advances published new progress about 5153-73-1. 5153-73-1 belongs to nitriles-buliding-blocks, auxiliary class Nitrile,Alkenyl,Nitro Compound,Benzene, name is (E)-4-(2-Nitrovinyl)benzonitrile, and the molecular formula is C9H6N2O2, Recommanded Product: (E)-4-(2-Nitrovinyl)benzonitrile.
Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts