Becker, Peter published the artcileDesigning Homogeneous Bromine Redox Catalysis for Selective Aliphatic C-H Bond Functionalization, HPLC of Formula: 73217-11-5, the main research area is sulfonamide bromine mCPBA light oxidation intramol amination catalyst; pyrrolidine sulfonyl preparation; oxaziridine sulfonyl preparation; C−H functionalization; Hofmann-Löffler reaction; amination; bromine; catalysis.
The potential of homogeneous oxidation catalysis employing bromine has remained largely unexplored. We herein show that the combination of a tetraalkylammonium bromide and meta-chloroperbenzoic acid offers a unique catalyst system for the convenient and selective oxidation of saturated C(sp3)-H bonds upon photochem. initiation with day light. This approach enables remote, intramol., position-selective C-H amination as demonstrated for 20 different examples. For the first time, an N-halogenated intermediate was isolated as the active catalyst state in a catalytic Hofmann-Loffler reaction. In addition, an expeditious one-pot synthesis of N-sulfonyl oxaziridines from N-sulfonamides was developed and exemplified for 15 transformations. These pioneering examples provide a change in paradigm for mol. catalysis with bromine.
Angewandte Chemie, International Edition published new progress about Amination (intramol.). 73217-11-5 belongs to class nitriles-buliding-blocks, name is 2-(2-(Bromomethyl)phenyl)acetonitrile, and the molecular formula is C9H8BrN, HPLC of Formula: 73217-11-5.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts