Lai, Calvine published the artcileAdvances in Stereoselective Iron(II)-Catalyzed Synthesis of Sulfilimines with N-Mesyloxycarbamates, HPLC of Formula: 100-70-9, the main research area is sulfilimine preparation enantioselective diastereoselective; thioether mesyloxycarbamate amination iron catalyst stereoselective.
A stereoselective amination of thioethers R1SR2 to access sulfilimines (R)-R1R2SNC(O)OR3 [R1 = Ph, naphthalen-2-yl, thiophen-2-yl, etc., R2 = Me, Et, R3 = (4-methylphenyl)methyl, diphenylmethyl, 2,2,2-trichloroethyl, etc.] using N-mesyloxycarbamates MsOHNC(O)OR3 in a catalytic system composed of iron(II) chloride and a pyridine oxazoline (PyOX) ligand, e.g., (S)-5,5-dimethyl-4-phenyl-2-(pyridin-2-yl)-4,5-dihydrooxazole, has been developed. The reaction proceeds with modest to good yields and selectivities (up to 86:14 d.r. and 72:28 e.r.). Selectivity was controlled by both the structure of the chiral ligand and the amination reagent.
Helvetica Chimica Acta published new progress about Amination catalysts (stereoselective). 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, HPLC of Formula: 100-70-9.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts