The Cascade Methylation/Cyclization of ortho-Cyanoarylacrylamides with Dicumyl Peroxide was written by Yang, Tao;Xia, Wen-Jin;Zhou, Bin;Xin, Yangchun;Shen, Yuehai;Li, Ya-Min. And the article was included in European Journal of Organic Chemistry in 2019.SDS of cas: 1483-54-1 This article mentions the following:
A radical cascade methylation/cyclization of ortho-cyanoarylacrylamides was developed by utilizing dicumyl peroxide as a methylation reagent. This transformation provides a simple and straight forward approach to methylated quinoline-2,4(1H,3H)-diones, and exhibits a wide substrate scope. Furthermore, this reaction could be readily scaled up. A possible mechanism is also proposed. In the experiment, the researchers used many compounds, for example, 2-Amino-4-(trifluoromethyl)benzonitrile (cas: 1483-54-1SDS of cas: 1483-54-1).
2-Amino-4-(trifluoromethyl)benzonitrile (cas: 1483-54-1) belongs to nitriles. Nitrile compounds can be prepared by the incorporation of a cyanide source through C閳ユ弲 bond formation or by dehydration of primary carboxamides. In addition, Nitriles can react with alkynes, which leads to an increase in carbon chain length (carbocyanation).SDS of cas: 1483-54-1
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts