Core-shell structured mesoporous silica: a new immobilized strategy for rhodium catalyzed asymmetric transfer hydrogenation was written by Zhang, Huaisheng;Jin, Ronghua;Yao, Hui;Tang, Shuang;Zhuang, Jinglan;Liu, Guohua;Li, Hexing. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2012.Reference of 101219-69-6 This article mentions the following:
A core-shell structured heterogeneous rhodium catalyst exhibited excellent catalytic activity and enantioselectivity in asym. transfer hydrogenation of aromatic ketones in aqueous medium, which could be recovered easily and used repetitively twelve times without affecting obviously its enantioselectivity. In the experiment, the researchers used many compounds, for example, (R)-4-(1-Hydroxyethyl)benzonitrile (cas: 101219-69-6Reference of 101219-69-6).
(R)-4-(1-Hydroxyethyl)benzonitrile (cas: 101219-69-6) belongs to nitriles. Nitrile function is a very important functional group because it can be manipulated to other functional groups such as carboxylic acid by hydrolysis or amine by reduction, respectively. Nitrile groups in organic compounds can undergo a variety of reactions depending on the reactants or conditions. A nitrile group can be hydrolyzed, reduced, or ejected from a molecule as a cyanide ion.Reference of 101219-69-6
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts