The novel reaction of ketones with o-oxazoline-substituted anilines was written by Luo, Fen-Tair;Ravi, Vija K.;Xue, Cuihua. And the article was included in Tetrahedron in 2006.Synthetic Route of C7H5ClN2 This article mentions the following:
A variety of ketones reacted with o-oxazoline-substituted anilines in the presence of catalytic amount of p-toluenesulfonic acid in dry n-butanol to form 4-amino-substituted quinolines or 4-quinolones in fair to good yields. In the experiment, the researchers used many compounds, for example, 2-Amino-3-chlorobenzonitrile (cas: 53312-77-9Synthetic Route of C7H5ClN2).
2-Amino-3-chlorobenzonitrile (cas: 53312-77-9) belongs to nitriles. Nitrile function is a very important functional group because it can be manipulated to other functional groups such as carboxylic acid by hydrolysis or amine by reduction, respectively. Alkyl nitriles are sufficiently acidic to undergo deprotonation of the C-H bond adjacent to the CN group.Strong bases are required, such as lithium diisopropylamide and butyl lithium. The product is referred to as a nitrile anion. Synthetic Route of C7H5ClN2
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts