Ruthenium-Catalyzed Direct Reductive Amination in HCOOH/NEt3 Mixture was written by Zhu, Mengping. And the article was included in Catalysis Letters in 2014.Reference of 10282-32-3 This article mentions the following:
Abstract: A one-pot direct reductive amination of aldehydes with primary and secondary amines using Noyori’s catalyst (η6-arene)Ru(H)TsDPEN in neat HCOOH/NEt3 mixture has been developed. The catalyst formed in situ allows full conversion of aldehydes with high selectivities towards the desired amine products within hours or even minutes at room temperature For aromatic aldehydes, both 5:2 and 5:3 HCOOH/NEt3 mixtures prove to be suitable reaction media, with the former affording higher selectivities while the latter leading to much faster reaction rates. For aliphatic aldehydes, the 5:3 HCOOH/NEt3 mixture gives much higher selectivities due to the minimal loss from aldol condensation. This method has great application potential for the synthesis of amine products given the mild conditions. Graphical Abstract: [Figure not available: see full text.]. In the experiment, the researchers used many compounds, for example, 4-(Benzylamino)benzonitrile (cas: 10282-32-3Reference of 10282-32-3).
4-(Benzylamino)benzonitrile (cas: 10282-32-3) belongs to nitriles. Nitrile carbon shifts are in the range of 115–125 ppm whereas in isonitriles the shifts are around 155–165 ppm. Nitrile groups in organic compounds can undergo a variety of reactions depending on the reactants or conditions. A nitrile group can be hydrolyzed, reduced, or ejected from a molecule as a cyanide ion.Reference of 10282-32-3
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts