Synthesis of 2-azo-3-cyano-5-carbethoxy thiophene derivatives and their application on polyester fibers was written by Sabnis, Ram W.;Rangnekar, Dinesh W.. And the article was included in Journal of Chemical Technology and Biotechnology in 1990.Application In Synthesis of Ethyl 5-amino-4-cyano-3-(2-ethoxy-2-oxoethyl)thiophene-2-carboxylate This article mentions the following:
Synthesis of 2-(hetaryl or aryl)-azo thiophene derivatives was achieved by diazotization of Et 2-amino-3-cyano-5-carbethoxythiophene-4-acetate (I) using nitrosylsulfuric acid and coupling with suitable heterocyclic hydroxy and N,N-dialkyl-substituted aryl amines. I was synthesized in one pot and in excellent yield from di-Et acetonedicarboxylate, S and malonitrile, using HNEt2 as a catalyst, following the Gewald synthesis. The spectral properties of these dyes were studied. The dyes when applied as disperse dyes on polyester fibers gave excellent results. In the experiment, the researchers used many compounds, for example, Ethyl 5-amino-4-cyano-3-(2-ethoxy-2-oxoethyl)thiophene-2-carboxylate (cas: 58168-20-0Application In Synthesis of Ethyl 5-amino-4-cyano-3-(2-ethoxy-2-oxoethyl)thiophene-2-carboxylate).
Ethyl 5-amino-4-cyano-3-(2-ethoxy-2-oxoethyl)thiophene-2-carboxylate (cas: 58168-20-0) belongs to nitriles. Nitriles are polar, as indicated by high dipole moments. As liquids, they have high relative permittivities, often in the 30s. In addition, Nitriles can react with alkynes, which leads to an increase in carbon chain length (carbocyanation).Application In Synthesis of Ethyl 5-amino-4-cyano-3-(2-ethoxy-2-oxoethyl)thiophene-2-carboxylate
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts