Preparation and characterization of ZnO/nanoclinoptilolite as a new nanocomposite and studying its catalytic performance in the synthesis of 2-aminothiophenes via Gewald reaction was written by Javadi, Farzad;Tayebee, Reza. And the article was included in Microporous and Mesoporous Materials in 2016.Category: nitriles-buliding-blocks This article mentions the following:
The nanocomposite ZnO/nanoclinoptilolite (ZnO/NCP) was prepared and used as an efficient heterogeneous catalyst in the synthesis of 2-aminotiophene derivatives by Gewald reaction. The nanocomposite was prepared through impregnation of the nanoclinoptilolite (NCP) surface with zinc chloride solution through Zn2+ ion exchange, followed by calcination at 500° for 24 h. The synthesized nanocomposite was characterized by XRD, SEM, FESEM, FT-IR, ICP, and nitrogen adsorption/desorption isotherm. The obtained catalytic assays demonstrated that the catalytic activity of ZnO/NCP nanocomposite was increased with enhancing the amount of ZnO. Moreover, the prepared nanocomposite showed very good stability and reusability in the titled synthetic method under aerobic and mild conditions. In the experiment, the researchers used many compounds, for example, 2-Amino-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carbonitrile (cas: 70291-62-2Category: nitriles-buliding-blocks).
2-Amino-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carbonitrile (cas: 70291-62-2) belongs to nitriles. There has been no report on the microbial biosynthesis of nitriles and the physiological function of such enzymes, nor was it not even known whether aliphatic and aromatic nitriles are biological compounds or just petrochemicals. Alkyl nitriles are sufficiently acidic to undergo deprotonation of the C-H bond adjacent to the CN group.Strong bases are required, such as lithium diisopropylamide and butyl lithium. The product is referred to as a nitrile anion. Category: nitriles-buliding-blocks
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts