Selective deoxygenative alkylation of alcohols via photocatalytic domino radical fragmentations was written by Guo, Hong-Mei;Wu, Xuesong. And the article was included in Nature Communications in 2021.Related Products of 24056-34-6 This article mentions the following:
A one-pot strategy for deoxygenative Giese reaction of alcs. with electron-deficient alkenes, by using xanthate salts as alc.-activating groups for radical generation under visible-light photoredox conditions in the presence of triphenylphosphine were reported. The convenient generation of xanthate salts and high reactivity of sequential C-S/C-O bond homolytic cleavage enable efficient deoxygenation of primary, secondary and tertiary alcs. with diverse functionality and structure to generate the corresponding alkyl radicals, including Me radical. Moreover, chemoselective radical monodeoxygenation of diols was achieved via selective formation of xanthate salts. In the experiment, the researchers used many compounds, for example, 4-Hydroxycyclohexanecarbonitrile (cas: 24056-34-6Related Products of 24056-34-6).
4-Hydroxycyclohexanecarbonitrile (cas: 24056-34-6) belongs to nitriles. Nitriles are polar, as indicated by high dipole moments. As liquids, they have high relative permittivities, often in the 30s. Alkyl nitriles are sufficiently acidic to undergo deprotonation of the C-H bond adjacent to the CN group.Strong bases are required, such as lithium diisopropylamide and butyl lithium. The product is referred to as a nitrile anion. Related Products of 24056-34-6
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts