Oxidation of alcohols by transition metal complexes. Part III. The reduction of aldimines by hydrogen transfer from propan-2-ol catalyzed by rhodium complexes was written by Grigg, Ronald;Mitchell, Thomas R. B.;Tongpenyai, Ngampong. And the article was included in Synthesis in 1981.Category: nitriles-buliding-blocks This article mentions the following:
Benzaldimines 4-RC6H4CH:NCH2Ph (R = H, Me, MeO, Cl, CF3) and I (R1 = H, MeO, Cl, CF3, cyano; R2 = H, MeO, Cl, CF3, cyano) reacted with Me2CHOH and a Rh complex to yield the resp. 4-RC6H4CH2NHCH2Ph and II. A mixture of PhCH:NCH2Ph, RhCl(PPh3)3, and Na2CO3 in Me2CHOH was refluxed 60 min to give ∼90% (Ph2CH2)2NH. In the experiment, the researchers used many compounds, for example, 4-(Benzylamino)benzonitrile (cas: 10282-32-3Category: nitriles-buliding-blocks).
4-(Benzylamino)benzonitrile (cas: 10282-32-3) belongs to nitriles. Nitrile function is a very important functional group because it can be manipulated to other functional groups such as carboxylic acid by hydrolysis or amine by reduction, respectively. Alkyl nitriles are sufficiently acidic to undergo deprotonation of the C-H bond adjacent to the CN group.Strong bases are required, such as lithium diisopropylamide and butyl lithium. The product is referred to as a nitrile anion. Category: nitriles-buliding-blocks
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts