Phenanthrene Synthesis by Palladium(II)-Catalyzed γ-C(sp2)-H Arylation, Cyclization, and Migration Tandem Reaction was written by Gou, Bo-Bo;Yang, Hui;Sun, Huai-Ri;Chen, Jie;Wu, Junliang;Zhou, Ling. And the article was included in Organic Letters in 2019.Computed Properties of C11H13NO This article mentions the following:
Phenanthrene is an important structural motif in chem. and materials science, and many synthetic routes have been developed to construct its skeleton. However, synthesis of unsym. phenanthrenes remains a challenge. Here, an efficient one-pot tandem reaction for the preparation of phenanthrenes via sequential γ-C(sp2)-H arylation, cationic cyclization, dehydration, and 1,2-migration was developed. A wide range of sym. and unsym. phenanthrenes with diversified functional groups were synthesized with good to excellent yields. In the experiment, the researchers used many compounds, for example, 2-(4-Methoxyphenyl)-2-methylpropanenitrile (cas: 5351-07-5Computed Properties of C11H13NO).
2-(4-Methoxyphenyl)-2-methylpropanenitrile (cas: 5351-07-5) belongs to nitriles. Nitrile compounds can be prepared by the incorporation of a cyanide source through C–C bond formation or by dehydration of primary carboxamides. Nitriles are susceptible to hydrogenation over diverse metal catalysts. The reaction can afford either the primary amine (RCH2NH2) or the tertiary amine ((RCH2)3N), depending on conditions.Computed Properties of C11H13NO
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts