Gamez, Patrick et al. published their research in Tetrahedron Letters in 1993 | CAS: 101219-69-6

(R)-4-(1-Hydroxyethyl)benzonitrile (cas: 101219-69-6) belongs to nitriles. Nitrile function is a very important functional group because it can be manipulated to other functional groups such as carboxylic acid by hydrolysis or amine by reduction, respectively. In conventional organic reductions, nitrile is reduced by treatment with lithium aluminium hydride to the amine. Reduction to the imine followed by hydrolysis to the aldehyde takes place in the Stephen aldehyde synthesis, which uses stannous chloride in acid.Quality Control of (R)-4-(1-Hydroxyethyl)benzonitrile

Enantioselective catalytic reduction of ketones using C2-symmetric diamines as chiral ligands was written by Gamez, Patrick;Fache, Fabienne;Mangeney, Pierre;Lemaire, Marc. And the article was included in Tetrahedron Letters in 1993.Quality Control of (R)-4-(1-Hydroxyethyl)benzonitrile This article mentions the following:

The catalytic enantioselective reduction of various prochiral ketones is reported using C2-sym. diamines as ligands. Up to 99% e.e. at 100% conversion are obtained. In the experiment, the researchers used many compounds, for example, (R)-4-(1-Hydroxyethyl)benzonitrile (cas: 101219-69-6Quality Control of (R)-4-(1-Hydroxyethyl)benzonitrile).

(R)-4-(1-Hydroxyethyl)benzonitrile (cas: 101219-69-6) belongs to nitriles. Nitrile function is a very important functional group because it can be manipulated to other functional groups such as carboxylic acid by hydrolysis or amine by reduction, respectively. In conventional organic reductions, nitrile is reduced by treatment with lithium aluminium hydride to the amine. Reduction to the imine followed by hydrolysis to the aldehyde takes place in the Stephen aldehyde synthesis, which uses stannous chloride in acid.Quality Control of (R)-4-(1-Hydroxyethyl)benzonitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts