2-Substituted 8,9-cycloalkathieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5(6H)-ones was written by Chernyuk, O. M.;Tolmachova, V. S.;Vovk, M. V.. And the article was included in Ukrainskii Khimicheskii Zhurnal (Russian Edition) in 2009.Recommanded Product: 70291-62-2 This article mentions the following:
A series of cycloalkane-fused thieno[3.2-e][1,2,4]triazolo[1,5-c]pyrimidinones I [R1R2 = (CH2)3, (CH2)4, CH2CHMeCH2CH2, (CH2)5; R3 = Ph, 4-FC6H4, 2-furyl, 3-pyridyl, etc.] was synthesized by condensation of N-(cyanothienyl) carbamates II with carboxylic acids hydrazides R3CONHNH2. In the experiment, the researchers used many compounds, for example, 2-Amino-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carbonitrile (cas: 70291-62-2Recommanded Product: 70291-62-2).
2-Amino-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carbonitrile (cas: 70291-62-2) belongs to nitriles. The R-C-N bond angle in and nitrile is 180° which give a nitrile functional group a linear shape. Both the carbon and the nitrogen are sp hydridized which leaves them both with two p orbitals which overlap to form the two π bond in the triple bond. Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. Both routes are green in the sense that they do not generate stoichiometric amounts of salts.Recommanded Product: 70291-62-2
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts