4-Amino-6-(piperidin-1-yl)pyrimidine-5-carbonitrile was written by Bhat, Radhika;Shraddha, K. N.;Begum, Noor Shahina. And the article was included in IUCrData in 2020.Recommanded Product: 60025-09-4 This article mentions the following:
In the title compound, C10H13N5, the piperidine ring adopts a chair conformation with the exocyclic N-C bond in an axial orientation, and the dihedral angle between the mean planes of piperidine and pyrimidine rings is 49.57 (11)°. A short intramol. C-H···N contact generates an S(7) ring. In the crystal, N-H···N hydrogen bonds link the mols. into (100) sheets and a weak aromatic π-π stacking interaction is observed [centroid-centroid separation = 3.5559 (11) Å] between inversion-related pyrimidine rings. In the experiment, the researchers used many compounds, for example, 4-Amino-6-chloropyrimidine-5-carbonitrile (cas: 60025-09-4Recommanded Product: 60025-09-4).
4-Amino-6-chloropyrimidine-5-carbonitrile (cas: 60025-09-4) belongs to nitriles. Nitrile function is a very important functional group because it can be manipulated to other functional groups such as carboxylic acid by hydrolysis or amine by reduction, respectively. In addition, Nitriles can react with alkynes, which leads to an increase in carbon chain length (carbocyanation).Recommanded Product: 60025-09-4
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts