McEwen, Charles N. published the artcileSublimation Driven Ionization for Use in Mass Spectrometry: Mechanistic Implications, Synthetic Route of 91-15-6, the main research area is mass spectrometry ionization sublimation driven.
Sublimation has been known at least since the middle ages. This process is frequently taught in schools through the use of phase diagrams. Astonishingly, such a well-known process appears to still harbor secrets. Under conditions in which compound sublimation occurs, gas-phase ions are frequently detected using mass spectrometry. This was exploited in matrix-assisted ionization in vacuum (vMAI) by adding analyte to subliming compounds used as matrixes. Good vMAI matrixes were those that ionize the added analyte with high sensitivity, but even matrixes that fail this test often produce ions of likely matrix impurities suggesting that they may be good matrixes for some compound types. We also show that binary matrixes may be manipulated to provide desired properties such as fast analyses and improved sensitivity. These results imply that sublimation in some cases is more complicated than just mols. leaving a surface and that understanding the phys. force responsible, and how the nonvolatile compound becomes charged, could lead to improved ionization efficiency for mass spectrometry. Here we provide insights into this process and an explanation of why this unexpected phenomenon has not previously been reported.
Journal of the American Society for Mass Spectrometry published new progress about Impurities. 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Synthetic Route of 91-15-6.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts