Jiang, Huanfeng’s team published research in Organic Letters in 21 | CAS: 612-13-5

Organic Letters published new progress about 612-13-5. 612-13-5 belongs to nitriles-buliding-blocks, auxiliary class Organic Pigment, name is 2-(Chloromethyl)benzonitrile, and the molecular formula is C8H6ClN, Synthetic Route of 612-13-5.

Jiang, Huanfeng published the artcileA Three-Phase Four-Component Coupling Reaction: Selective Synthesis of o-Chloro Benzoates by KCl, Arynes, CO2, and Chloroalkanes, Synthetic Route of 612-13-5, the publication is Organic Letters (2019), 21(2), 345-349, database is CAplus and MEDLINE.

Chloroalkyl and benzylic o-chlorobenzoates such as I were prepared by three-phase, four-component coupling reactions of o-trimethylsilylaryl triflates, KCl, CO2, and dichloroalkanes such as 1,2-dichloroethane or benzylic chlorides, incorporating both chloride and CO2 simultaneously. I underwent nucleophilic substitution reactions at the alkyl chloride moiety and a Suzuki coupling reaction at its aryl chloride moiety.

Organic Letters published new progress about 612-13-5. 612-13-5 belongs to nitriles-buliding-blocks, auxiliary class Organic Pigment, name is 2-(Chloromethyl)benzonitrile, and the molecular formula is C8H6ClN, Synthetic Route of 612-13-5.

Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts