Chen, Zhen’s team published research in Organic Letters in 20 | CAS: 5153-73-1

Chen, Zhen published the artcileTransition-Metal-Free [3 + 2] Cycloaddition of Nitroolefins and Diazoacetonitrile: A Facile Access to Multisubstituted Cyanopyrazoles, Synthetic Route of 5153-73-1, the publication is Organic Letters (2018), 20(7), 2120-2124, database is CAplus and MEDLINE.

Nitroalkenes such as β-nitrostyrenes (E)-RCH:CHNO₂ [R = Ph, 4-MeC₆H₄, 4-MeOC₆H₄, 4-Me₂NC₆H₄, 4-FC₆H₄, 4-ClC₆H₄, 4-BrC₆H₄, 4-F₃CC₆H₄, 4-NCC₆H₄, 3-MeOC₆H₄, 2-MeOC₆H₄, 2-BrC₆H₄, 1-naphthyl, 2-naphthyl, 9-anthracenyl, 2-furyl, 2-thienyl, (E)-R¹CH:CH, PhCC, PhCH₂CH₂, Bu, i-Bu, cyclohexyl; R¹ = Ph, 4-MeOC₆H₄, 2-O₂NC₆H₄] underwent metal-free regioselective [3+2]-cycloaddition reactions with diazoacetonitrile N₂:CHCN either used sep. or generated in situ from aminoacetonitrile hydrochloride with Cs₂CO₃ in THF to give 3-pyrazolecarbonitriles such as I [R = Ph, 4-MeC₆H₄, 4-MeOC₆H₄, 4-Me₂NC₆H₄, 4-FC₆H₄, 4-ClC₆H₄, 4-BrC₆H₄, 4-F₃CC₆H₄, 4-NCC₆H₄, 3-MeOC₆H₄, 2-MeOC₆H₄, 2-BrC₆H₄, 1-naphthyl, 2-naphthyl, 9-anthracenyl, 2-furyl, 2-thienyl, (E)-R¹CH:CH, PhCC, PhCH₂CH₂, Bu, i-Bu, cyclohexyl; R¹ = Ph, 4-MeOC₆H₄, 2-O₂NC₆H₄] in 55-93% yields. The cycloaddition reaction was also performed in tandem with regioselective N-alkylation reactions with MeI or PhCH₂Br to yield 1-methyl- or 1-benzyl-3-pyrazolecarbonitriles in 31-73% yields with 10-48% of the 2-alkyl-3-pyrazolecarbonitrile regioisomers (<25% yields in ten of twelve cases). Diazoacetonitrile is potentially explosive and should be handled with caution.

Organic Letters published new progress about 5153-73-1. 5153-73-1 belongs to nitriles-buliding-blocks, auxiliary class Nitrile,Alkenyl,Nitro Compound,Benzene, name is (E)-4-(2-Nitrovinyl)benzonitrile, and the molecular formula is C9H6N2O2, Synthetic Route of 5153-73-1.

Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts