Chen, Zhen published the artcileUse of a Traceless Activating and Directing Group for the Construction of Trifluoromethylpyrazoles: One-Pot Transformation of Nitroolefins and Trifluorodiazoethane, Quality Control of 5153-73-1, the publication is Angewandte Chemie, International Edition (2017), 56(16), 4569-4574, database is CAplus and MEDLINE.
We disclose an efficient one-pot transformation of trifluorodiazoethane and higher perfluorinated homologues with various nitroolefins. This method takes advantage of the nitro group as a traceless activating and directing group (TADG) that is released in the aromatization step to produce 4-substituted 3-perfluoroalkyl pyrazoles with complete regioselectivity [e.g, trans-β-nitrostyrene + CF3CHN2 → pyrazole I (89%) in presence of Ag2O and Na3PO4]. The potential of this method is further demonstrated by the synthesis of penthiopyrad. Safety: 2,2,2-trifluorodiazoethane is potentially explosive.
Angewandte Chemie, International Edition published new progress about 5153-73-1. 5153-73-1 belongs to nitriles-buliding-blocks, auxiliary class Nitrile,Alkenyl,Nitro Compound,Benzene, name is (E)-4-(2-Nitrovinyl)benzonitrile, and the molecular formula is C9H6N2O2, Quality Control of 5153-73-1.
Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts