Wit, J. G. published the artcileMonophenolic metabolites of the herbicide, 2,6-dichlorobenzonitrile, in animals as uncouplers of oxidative phosphorylation, Safety of 2,6-Dichloro-3-hydroxybenzonitrile, the publication is Biochemical Journal (1966), 707-10, database is CAplus and MEDLINE.
Both monophenolic metabolites of 2,6-dichlorobenzonitrile (2,6-dichloro-3-hydroxybenzonitrile and its 4-hydroxy analog) added to starved yeast cells incubated with a limited quantity of glucose caused a significant rise in O consumption of the cells. The same compounds induce ATPase activity in isolated intact rat liver mitochondria. The possible role of the hydroxylation of 2,6-dichlorobenzonitrile in mammals, in relation to hepatic injury, is discussed.
Biochemical Journal published new progress about 3336-34-3. 3336-34-3 belongs to nitriles-buliding-blocks, auxiliary class Chloride,Nitrile,Benzene,Phenol, name is 2,6-Dichloro-3-hydroxybenzonitrile, and the molecular formula is C6H10O2S, Safety of 2,6-Dichloro-3-hydroxybenzonitrile.
Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts