Wang, Hong-xue’s team published research in Yingyong Huagong in 41 | CAS: 612-13-5

Yingyong Huagong published new progress about 612-13-5. 612-13-5 belongs to nitriles-buliding-blocks, auxiliary class Organic Pigment, name is 2-(Chloromethyl)benzonitrile, and the molecular formula is C8H5IO, Recommanded Product: 2-(Chloromethyl)benzonitrile.

Wang, Hong-xue published the artcileStudy of scale up of fluorescent whitening agent ER-I, Recommanded Product: 2-(Chloromethyl)benzonitrile, the publication is Yingyong Huagong (2012), 41(9), 1658-1660, database is CAplus.

The fluorescent brightener ER-I was synthesized through Abuzov esterification and Witting condensation with the raw material tri-Et phosphite, 2-(chloromethyl) benzonitrile and 1, 4-phthalaldehyde. The influence factors such as reaction temperature, feeding method and the ratio of raw material were researched in detail. The optimum reaction condition was as follows: when the ratio of tri-Et phosphite : benzyl chloride 1.1:1.0 was used, temperature of feed was 140°C, the reaction time was 9 h, and the total yield 93%. The stabilization of technol. condition was confirmed by 6 time tests.

Yingyong Huagong published new progress about 612-13-5. 612-13-5 belongs to nitriles-buliding-blocks, auxiliary class Organic Pigment, name is 2-(Chloromethyl)benzonitrile, and the molecular formula is C8H5IO, Recommanded Product: 2-(Chloromethyl)benzonitrile.

Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts