Spencer, John’s team published research in Tetrahedron Letters in 53 | CAS: 5098-14-6

Tetrahedron Letters published new progress about 5098-14-6. 5098-14-6 belongs to nitriles-buliding-blocks, auxiliary class Nitrile,Salt,Sulfonic acid,Amine,Benzene, name is 2-Aminomalononitrile 4-methylbenzenesulfonate, and the molecular formula is C12H13BrN2O2, Application of 2-Aminomalononitrile 4-methylbenzenesulfonate.

Spencer, John published the artcileMicrowave-mediated synthesis and manipulation of a 2-substituted-5-aminooxazole-4-carbonitrile library, Application of 2-Aminomalononitrile 4-methylbenzenesulfonate, the publication is Tetrahedron Letters (2012), 53(13), 1656-1659, database is CAplus.

A 2-substituted 5-aminooxazole-4-carbonitrile library has been synthesized and modified via microwave-mediated and flow chemistries. One synthesized compound, 5-(1H-pyrrol-1-yl)-4-(1H-tetrazol-5-yl)-2-(thien-2-yl)oxazole, contains three distinct heterocycles attached to the central oxazole core, highlighting the structural diversity of this approach. Three oxazoles had micromolar ki values against cannabinoid (CB1/CB2) receptors.

Tetrahedron Letters published new progress about 5098-14-6. 5098-14-6 belongs to nitriles-buliding-blocks, auxiliary class Nitrile,Salt,Sulfonic acid,Amine,Benzene, name is 2-Aminomalononitrile 4-methylbenzenesulfonate, and the molecular formula is C12H13BrN2O2, Application of 2-Aminomalononitrile 4-methylbenzenesulfonate.

Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts