Zhang, Wenjun’s team published research in Synthetic Communications in 47 | CAS: 612-13-5

Synthetic Communications published new progress about 612-13-5. 612-13-5 belongs to nitriles-buliding-blocks, auxiliary class Organic Pigment, name is 2-(Chloromethyl)benzonitrile, and the molecular formula is C5H5BrN2, SDS of cas: 612-13-5.

Zhang, Wenjun published the artcileSynthesis of aryl acetamides by aminocarbonylation of benzylic chlorides using carbamoylsilane as an amide source, SDS of cas: 612-13-5, the publication is Synthetic Communications (2017), 47(7), 704-709, database is CAplus.

Using N-methyl-N-(1-phenyl)ethylcarbamoyl(trimethyl)silane as an amide source, the direct transformation of benzylic chlorides into the corresponding aryl acetamides through palladium-catalyzed aminocarbonylation is described. The electronic property and the relative position of substituents on the aromatic ring impact the coupling efficiency.

Synthetic Communications published new progress about 612-13-5. 612-13-5 belongs to nitriles-buliding-blocks, auxiliary class Organic Pigment, name is 2-(Chloromethyl)benzonitrile, and the molecular formula is C5H5BrN2, SDS of cas: 612-13-5.

Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts