Zhang, Sheng’s team published research in Journal of Organic Chemistry in 82 | CAS: 612-13-5

Journal of Organic Chemistry published new progress about 612-13-5. 612-13-5 belongs to nitriles-buliding-blocks, auxiliary class Organic Pigment, name is 2-(Chloromethyl)benzonitrile, and the molecular formula is C7H5Cl2NO, Category: nitriles-buliding-blocks.

Zhang, Sheng published the artcilePalladium-Catalyzed sp2-sp3 Coupling of Chloromethylarenes with Allyltrimethoxysilane: Synthesis of Allyl Arenes, Category: nitriles-buliding-blocks, the publication is Journal of Organic Chemistry (2017), 82(11), 5974-5980, database is CAplus and MEDLINE.

Palladium-catalyzed remote sp2-sp3 coupling reaction of chloromethylarenes with allyltrimethoxysilane is described in this work. The allylation reaction regioselectively occurred on the para-positions of 1-(chloromethyl)naphthalenes and benzyl chlorides to form new C(sp2)-C(sp3) bonds. The reaction proceeds smoothly under mild conditions to produce allyl arenes in moderate to excellent yields.

Journal of Organic Chemistry published new progress about 612-13-5. 612-13-5 belongs to nitriles-buliding-blocks, auxiliary class Organic Pigment, name is 2-(Chloromethyl)benzonitrile, and the molecular formula is C7H5Cl2NO, Category: nitriles-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts