Davison, K. L.’s team published research in Xenobiotica in 18 | CAS: 3336-34-3

Xenobiotica published new progress about 3336-34-3. 3336-34-3 belongs to nitriles-buliding-blocks, auxiliary class Chloride,Nitrile,Benzene,Phenol, name is 2,6-Dichloro-3-hydroxybenzonitrile, and the molecular formula is C7H3Cl2NO, Product Details of C7H3Cl2NO.

Davison, K. L. published the artcileIntermediary metabolism of 2,6-dichlorobenzonitrile (dichlobenil) in chickens and growth of chickens fed dichlobenil, Product Details of C7H3Cl2NO, the publication is Xenobiotica (1988), 18(8), 941-8, database is CAplus and MEDLINE.

Ten 14C-labeled metabolites were isolated from either bile (6 metabolites) or urine (7 metabolites) from chickens given single oral doses of 2,6-dichlorobenzo[14C]nitrile ([14C]dichlobenil). 2-(S-Glutathionyl)-3-hydroxy-6-chlorobenzo[14C]nitrile perfused through chicken kidneys in situ was excreted in urine from the perfused kidney (44% dose) as 2-mercapto-3-hydroxy-6-chlorobenzonitrile. Dichlobenil was fed at 0, 75, 150, or 225 ppm in the diet to broiler and laying strains of cockerels to determine biol. activity. Feed consumption and growth were not affected, but liver and kidney weights were higher in chicks fed the dichlobenil. The percentage of lipid or nitrogen in the livers and kidneys from chicks fed dichlobenil did not differ from controls and histol. or ultrastructural changes were not observed in these tissues.

Xenobiotica published new progress about 3336-34-3. 3336-34-3 belongs to nitriles-buliding-blocks, auxiliary class Chloride,Nitrile,Benzene,Phenol, name is 2,6-Dichloro-3-hydroxybenzonitrile, and the molecular formula is C7H3Cl2NO, Product Details of C7H3Cl2NO.

Referemce:
https://en.wikipedia.org/wiki/Nitrile,
Nitriles – Chemistry LibreTexts