Pietta, Piergiorgio published the artcilePurity assay of ketoprofen by high-performance liquid chromatography, Synthetic Route of 42872-30-0, the main research area is ketoprofen purity HPLC; liquid chromatog ketoprofen.
A HPLC method is suitable for purity assay of ketoprofen (I) [22071-15-4]. A Hibar LiChrocart RP C18 column with pH 2.7 MeCO-H2O (37:63) with 50% H3PO4 as eluent and detection at 254 nm are used. Et 4-hydroxybenzoate was chosen as internal standard Linearity was established by chromatographing standard solutions over the range 10-200 ng. The main impurity was 2-[3-(4-methylbenzoyl)phenyl]propionic acid (II) [107257-20-5] (â?.4%), while the content of 3-benzoylphenylacetic acid (III) [22071-22-3] was about 0.05%. 2-(3-Benzoylphenyl)propionitrile  [42872-30-0] was almost absent. The method is specific and reproducible.
Journal of Chromatography published new progress about ketoprofen purity HPLC; liquid chromatog ketoprofen. 42872-30-0 belongs to class nitriles-buliding-blocks, name is 2-(3-Benzoylphenyl)propanenitrile, and the molecular formula is C16H13NO, Synthetic Route of 42872-30-0.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts